The Grand Physician of Ming: From Clan Execution to Sole Chancellor

Transmigrating to the year before the founding of the Great Ming Dynasty, Hu Yi makes a terrifying discovery: his uncle is none other than Hu Weiyong. In history, the infamous "Hu Weiyong Case" became one of the Four Great Cases of the Hongwu era, prompting Emperor Zhu Yuanzhang to unleash a merciless purge that sent tens of thousands of heads rolling—including Hu Yi's entire extended clan of nine degrees. Shocked to find himself suddenly marked for execution by association, Hu Yi resolves to keep a low profile and survive. Fortunately, the dawn of the Ming Dynasty offers endless opportunities for those willing to climb, provided he plays his cards carefully. Starting as a humble itinerant doctor, Hu Yi only intends to save his own life. Yet his extraordinary medical skills propel him relentlessly upward. He rises from a sixth-rank official to Commandant-Escort and Grand Master of Splendid Happiness, eventually becoming the foremost physician of the empire and earning the supreme title of Senior Pillar of State—second only to the emperor himself. Through pioneering innovations like distilling alcohol for wound care, extracting garlic essence to heal soldiers, and introducing cowpox inoculations to eradicate smallpox, he secures his indispensable status at court. Before he realizes it, the man who merely wanted to survive has become the sole chancellor of the Great Ming, standing directly beside Emperor Zhu Yuanzhang and Crown Prince Zhu Biao. Beyond medicine, he champions the lifting of maritime trade bans despite fierce opposition from eastern Zhejiang officials, generating millions in annual customs revenue to save countless starving citizens. Living modestly on just thirty acres of mulberry fields gifted by his princess wife, his final testament humbly credits imperial grace for his rise, urging his descendants to remain diligent, protect Han orthodoxy, and ensure the sea routes to the West remain forever open.