Ore no Tomodachi ♂♀ ga Kawaisugite Komaru!

After a decade away, Amano returns to the city where he spent his childhood, expecting nothing more than a fresh start at a new school. However, his very first day as a transfer student takes an unexpected turn when he reunites with Yukio Sawatari, his former male childhood friend. To Amano's absolute shock, Yukio is no longer the boy he remembers—she has completely transformed into a girl. Yukio is just one of approximately 100,000 people worldwide affected by a mysterious condition known as "spontaneous isomerism metamorphosis," a sudden phenomenon that physically alters individuals from male to female. Despite the joy of reconnecting with an old friend after so many years, their reunion is complicated by Yukio's new reality. Having abruptly become a girl, she struggles to mask her deep embarrassment and vulnerability in everyday situations. As Amano navigates this bizarre new dynamic, he finds himself constantly caught off guard. His once-familiar childhood friend is now undeniably cute, leaving him flustered and unsure of how to act around her. Balancing the warmth of their long-standing bond with the overwhelming awkwardness of her sudden transformation, Amano must figure out how to support Yukio while dealing with his own conflicted feelings in this extraordinary new chapter of their lives.